Energetics and Lifestyle in Inherited Syndromes
Primary Investigator: Lauren Nye, MD
Co-Investigator: Jennifer Klemp, PhD
ELLIE'S Project aims to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation to develop ways to improve health outcomes.
One in eight women will develop breast cancer in her lifetime and just over 10% are in the setting of a hereditary breast cancer gene mutation. While genetic make-up is not a modifiable risk factor, obesity, nutrition, and physical activity are.
The impact of obesity, diet, and physical activity on breast cancer risk and outcomes need to be further characterized (weight, BMI, dietary habits) in genetic mutation carriers. The ELLIEs Project survey is collecting information on weight, physical activity, dietary habits, and metabolic risk factors in Hereditary Breast and Ovarian Cancer (HBOC) genetic mutation carriers.
ELLIE'S Project is currently recruiting survey participants!
The survey is open to any person, 18 years or older, who has a hereditary cancer genetic mutation in any of the following genes:
APC, ATM, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN4, CHEK2, DICER1, EPCAM, GREM1, HOXB13, MLH1, MRE11A, MSH2, MSH6, MUTYH, NBN, NF1, PALB2, PMS2, POLD1, POLE, PTEN, RAD50, RAD51C, RAD51D, SMAD4, SMARCA4, STK11, or TP53